Single-Cell RNA Sequencing vs. Bulk RNA Sequencing: Differences and Applications
In the rapidly advancing field of genomics, RNA sequencing (RNA-seq) has become an essential tool for understanding gene expression. Two primary approaches have emerged: single-cell RNA sequencing (scRNA-seq) and bulk RNA sequencing (bulk RNA-seq). Both methods offer unique insights into transcriptomics but differ significantly in their resolution, applications, and interpretation of data. This article explores the differences between scRNA-seq and bulk RNA-seq and highlights their respective applications in research and clinical settings.